MRI is very useful in the diagnosis of the most common renal masses.

The mesonephric duct, also known as Wolffian duct (WD), is a paired organ that during embryonic development forms as a part of urogenital system draining the primitive kidney (mesonephros) into the cloaca and giving off lateral branch forming the ureteric bud. In both male and female, WD develops into urinary bladder trigone and ureters.  In male, it has a fundamental role in reproductive organ’s formation (epididymis, ejaculatory duct, vas deferens, and seminal vesicle). In female, WDs degenerate, although inclusions cyst (e.g., Gardner’s cyst) or remnant may persist.     It is well known that WD anomalies are usually diagnosed in paediatric patient, but Radiologists can encounter these anomalies also in adult population. Due to close relationship between urinary and reproductive system development, congenital malformation (especially renal agenesia / malformation) is often associated to each other.  The aim of our work is to review embryology, anatomy and pathologies related to WD through a multi modal approach (Ultrasound US, Computed Tomography CT and Magnetic Resonance imaging MRI) to make Radiologists more familiar of such conditions and their associations and to guarantee a correct diagnosis not only in paediatric patients but also in the adult population.